Start REAPER, it will pick up the plugin automatically
Insert audio, for example a WAV file you want to use the plugin on
Either use the plugin on the entire file, or find the beginning and end locations in the file, then select-mark the region in between
Press SHIFT-S to separate the region into a separate item
Right click on the new item and select “Item properties”, then select “Take FX” at the bottom, then select the plugin
Set the plugin parameter as you need
You also need to remove “Fade in” and “Fade out” in the item properties of all items of the project
Select “Consolidate/Export tracks” in “File” menu to export the result as WAV file. Select “32 bit FP” as “Wave bit depth”.
ASIO4ALL
When I first installed REAPER everything worked right away and out of the box, however, after a while I got distorted audio when playing back, rendering was still ok. I never found how to fix this in the settings, but I remember having installed the Blackmagic Design Intensity Pro 4K capture card after which play back did not work as expected.
Remedy: I installed the ASIO4ALL Asio drivers for Windows audio which solved the problem.